Combination of Linkage and Association Studies for Brain Arteriovenous Malformation
نویسندگان
چکیده
منابع مشابه
Combination of linkage and association studies for brain arteriovenous malformation.
BACKGROUND AND PURPOSE Genetic factors for brain arteriovenous malformation are unexplored because of the low incidence of familial cases, albeit local and familial clustering. We used a combination of a linkage study and an association study to explore the genetic background. METHODS A genome-wide linkage analysis was performed in 12 patients from 6 unrelated families using the GENEHUNTER pr...
متن کاملRadiosurgical retreatment for brain arteriovenous malformation.
OBJECTIVE To analyze our experience with a second radiosurgical treatment for brain arteriovenous malformations (BAVMs) after an unsuccessful first radiosurgical treatment. METHODS Between 1993 and 2000, 242 patients were treated by the Toronto Sunnybrook Regional Cancer Center using a LINAC system. Fifteen of these patients required a second radiosurgical intervention due to the failure of t...
متن کاملOnyx in Brain Arteriovenous Malformation Embolisation.
INTRODUCTION Embolisation has long been used as an adjunct to surgical resection in the treatment of brain arteriovenous malformation (bAVM). The most commonly used embolic material, n-butylcyanoacrylate glue, requires experience and skill to handle its quick and unpredictable flow and polymerisation. A new liquid embolic agent, ethylene vinyl alcohol copolymer (Onyx), is less adhesive and poly...
متن کاملDeterminants of neurological outcome after surgery for brain arteriovenous malformation.
BACKGROUND AND PURPOSE We sought to define determinants of neurological deficit after surgery for brain arteriovenous malformation (AVM). METHODS One hundred twenty-four prospective patients (48% women, mean age 33 years) underwent microsurgical brain AVM resection. Patients were examined by 3 study neurologists immediately before surgery, postoperatively in-hospital, by in-person long-term f...
متن کاملPrevalence of brain arteriovenous malformations in first-degree relatives of patients with a brain arteriovenous malformation.
BACKGROUND AND PURPOSE It is uncertain whether familial occurrence of brain arteriovenous malformations (BAVMs) represents coincidental aggregation or a shared familial risk factor. We aimed to compare the prevalence of BAVMs in first-degree relatives (FDRs) of patients with BAVM and the prevalence in the general population. METHODS We sent a postal questionnaire to 682 patients diagnosed wit...
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ژورنال
عنوان ژورنال: Stroke
سال: 2007
ISSN: 0039-2499,1524-4628
DOI: 10.1161/01.str.0000260094.03782.59